Welcome to RADIATE. This research project is investigating the disabling, disfiguring limb anomaly Radial Dysplasia, which affects about 1:7,000 children born. The project has three main areas of study:
- Identifying more of the genetic changes that can cause radial dysplasia.
- Identifying differences in limb development, and how this might affect treatment.
- Identifying what treatment outcomes matter to children with radial dysplasia.
The project is a collaboration between Great Ormond St Hospital, led by Mr Bran Sivakumar and Miss Gill Smith, Consultant Hand Surgeons, and Professor Malcolm Logan at the Randall division, King’s College London. Radial dysplasia patients at Great Ormond Street will be invited to participate in one or more strands of the project. Hand trauma patients from the Royal Free and Chelsea & Westminster Hospitals will also be invited to participate, as normal controls.
The project is co-ordinated and conducted by George Murphy (Plastic Surgery Registrar and PhD student).
- This project was approved by the London Hampstead research ethics committee, on 9/12/2015 (15/LO/2085).
- The project has been adopted to the NIHR research portfolio (UKCRN ID 20411)
- Our protocol has been published on ClinicalTrials.gov (NCT02611089)
RADIATE 